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This historical 1943 image, which was provided by the Center for Disease Control's (that were consulting with a physician who was on the staff of a military ordnance factory during an investigation that was being carried out in order to determine the environmental presence of TNT (trinitrotoluene). Air and dust samples had been acquired inside the plant, whereupon, the results were discussed with the onsite doctor. A poisonous chemical, TNT will irritate the skin upon contact, and actually will change the skin’s color to a bright yellow-orange. Prolonged exposure leads to liver damage, anemia, enlargement of the spleen, and a compromised immune system, to name a few of its negative effects. Trinitrotoluene is also a known carcinogen. Occupational medicine is the branch of clinical medicine most active in the field of occupational health and safety. Its principal role is the provision of health advice to organizations and individuals, in order to ensure that the highest standards of workplace health and safety can be achieved, and maintained. In gaining a better understanding of workplace hazards, through hands-on and on-site information acquisition, protocol-formulating bodies such as NIOSH, are better able to create a safer workplace through substantiation of appropriate safety regulations.