Susan Cline, PhD

Susan ClineEducation

  • BA, Chemistry, University of Virginia
  • PhD, Biochemistry, Vanderbilt University
  • Postdoctoral Study, Biological Sciences, Stanford University

Research Interest

Dr. Cline’s previous research interests have included studies in mitochondrial DNA damage and its effects on gene expression. Currently, her interests are cognitive integration of clinical and biomedical sciences and professional identity formation in medical education.

Selected Publications

  • Cline, S. D., Simmons, J., Niederhoffer, E. C., Cruthirds, D. L., Arbor, S. C., Franklin, D. S., Abali, E., Bateman, R., Fontes, J., Lindsley, J., Rubenstein, P., Symes, K., and Viselli, S. (2019)  Teaching Biochemistry Students of Dentistry, Medicine, & Pharmacy: 7th International Conference of the Association of Biochemistry Educators (ABE) Tuscon, AZ, USA, May 5-9, 2019. Med Sci Educ. Online Nov 15, 2019. https://rdcu.be/b3XiP
  • Lindsley, J.E., Abali, E., Bikman, B.T., Cline, S.D., Fulton, T., Lopez, B., Rosenthal, O.D., Uhley, V.E., Weintraut, R.J., Williams, P.D., Wisco, J.J., and Thompson, K. (2017) What nutrition-related knowledge, skills and attitudes should medical students develop?  Med Sci Educ. 27:579-583.
  • Niederhoffer, E. C., Cline, S. D., Osheroff N., Simmons, J., Diekman, A. B, Franklin, D. S., Diekman, A. B., Abali, E., Bateman, R., Fontes, J., Lindsley, J., Pearson, D., Rubenstein, P., Slaughter, C. A., Bernstein, J. A., Hyland, K., Park, V., Sobering, A., Weiler, T. and Shoumita, D. (2017)  Teaching Biochemistry and Genetics to Students of Medicine, Pharmacy & Dentistry: 6th International Conference of the Association of Biochemistry Educators (ABE) Clearwater Beach, FL, USA, May 7-11, 2017. Med Sci Educ. 27:855-859.
  • Osheroff N., Niederhoffer, E. C., Sabina, R. L., Cline, S. D., Wimmer, M. J., Franklin, D. S., Diekman, A. B., Hogg, T., Kearney, K. R., King, S. C., Pearson, D., Slaughter, C. A., and Thompson, K. (2015)  Teaching Biochemistry to Students of Medicine, Pharmacy & Dentistry: 5th International Conference of the Association of Biochemistry Course Directors (ABCD) Santa Fe, NM, USA, May 3-7, 2015. Med Sci Educ. 25(4):473-477.
  • Cline, S. D. (2012) Mitochondrial DNA Damage and its Consequences for Mitochondrial Gene Expression. Biochim Biophys Acta. 1819:979-91.
  • Cameron, C. E. and Cline, S. D. (2012) Mitochondrial gene expression. Biochim Biophys Acta. 1819:913.
  • Horner, K. A., Gilbert, Y. E., and Cline, S. D. (2011) Widespread increases in malondialdehyde immunoreactivity in dopamine-rich and dopamine-poor regions of rat brain following multiple, high doses of methamphetamine. Front Syst Neurosci. 2011;5:27.
  • Cline, S. D., Lodeiro, M. F., Marnett, L. J., Cameron, C. E. and Arnold, J. J. (2010) Arrest of Human Mitochondrial RNA Polymerase Transcription by the Biological Aldehyde Adduct of DNA, M1dG.  Nucleic Acids Research 38, 7546-57.
  • Mayorov, V., Lowrey, A. J., Biousse, V, Newman, N. J., Cline, S. D., and Brown, M. D. (2008) Mitochondrial biochemistry in autosomal dominant optic atrophy. BMC Biochem 9:22.
  • Cline, S. D. and Hanawalt, P.C. (2006) Topoisomerase Deficiencies Subtly Enhance Global Genomic Repair of Ultraviolet-Induced DNA Damage in Saccharomyces cerevisiae. DNA Repair 5, 611-617.

Grants

  • Reactive Aldehyde DNA Damage in Mitochondrial Mutagenesis and Disease Pathophysiology
    PI: Susan Cline, PhD
    07/17/09 – 06/30/13
    NIH/NIGMS
    R15GM087681
    $226,815
  • Molecular Determinants of Mitochondrial Optic Atrophy
    PI: Susan Cline, PhD
    02/01/06 – 01/31/07
    NIH/NEI
    R01EY014393
    $245,215

Professional Involvement

  • Association of Biochemistry Educators (ABE), Board of Directors, 2013 – present
  • American Society for Biochemistry and Molecular Biology (ASBMB)
  • International Association of Medical Science Educators (IAMSE)

Contact Dr. Susan Cline


cline_sd@mercer.edu